Celmatix Launches Personalized Reproductive Medicine (PReM) Initiative to Decode Fertility Potential
October 19, 2015 – Celmatix, a personalized medicine company focused on fertility and women’s health, today announced the launch of the Personalized Reproductive Medicine (PReM) Initiative, an alliance created to investigate what an individual’s genetic signature and personalized metrics say about his or …
SERCA2a TREATMENT FOR PULMONARY HYPERTENSION
Pulmonary arterial hypertension (PAH) commonly results from heart failure in the left side of the heart or from a pulmonary embolism, when a blood clot in the leg travels to the lungs and cause blockages. When the lung is damaged from these …
Regeneron and Icahn School of Medicine at Mount Sinai Announce New Antibody Research Agreement
September 24, 2015 – Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) and The Experimental Therapeutics Institute (ETI) at the Icahn School of Medicine at Mount Sinai today announced that they have entered into an agreement with the goal of accelerating the discovery of fully …
GENE-SIGNATURE FOR DIAGNOSIS OF EARLY HEPATOCELLULAR CARCINOMA
The incidence of hepatocellular carcinoma (HCC) is 750,000 new cases globally, it is the second leading cause of cancer-related death and represents a major health problem. When identified at early stages, curative treatments such as resection, transplantation and percutaneous ablation are feasible. …
SOLUBLE INHIBITORS OF HIV-1 FROM CD8+ CELLS
CD8+ T-cells have been shown to secrete soluble factors that can effectively inhibit HIV replication. Researchers at Mount Sinai, led by Dr. Mary Klotman have identified and characterized key products from CD8+ cells that not only enhance the understanding of the HIV …
HYBRID FUSION PROTEIN TRANSCRIPTION REGULATOR – A NOVEL ANTIVIRAL THERAPY
Background: Two families of transcriptional regulators, members of the “signal transducers and activators of transcription” (STAT) and “interferon regulatory factor” (IRF) families, work in conjunction to establish a cascade of gene regulation and signal transduction events that lead to transcriptional activation of …
SLICE-SELECTIVE ADIABATIC MAGNETIZATION PREPARATION (SAMPA) FOR T2-WEIGHTED AND DIFFUSION-WEIGHTED IMAGING
Magnetic resonance (MR) imaging at high-fields (3-4.7T) and ultra-high fields (7T and above) leads to higher signal levels with improved image quality, but physical limitations still prevent these systems from being highly efficient. The gold standard for an important MRI method such …
SEMI-ADIABATIC SPECTRAL-SPATIAL SPECTROSCOPIC IMAGING (SASSI)
Proton magnetic resonance spectroscopic imaging (MRSI) can be used as a non-invasive technique for a variety of procedures such as differentiating radiation damage from brain tumors post-therapy, categorizing brain tumors, or investigating neurological and psychiatric diseases like Alzheimer’s and Parkinson’s Disease. However, …
MATCHED-PHASE SEMI-ADIABATIC MULTI-SLICE SPIN-ECHO PINS PULSE PAIR
There are still several challenges in acquiring high-quality MR images when using high magnetic field systems, such as the 7 Tesla. Three key issues prevent these systems from functioning at their highest potential: (1) nonuniformities in signal and contrast due to increased …
NeoStem, Inc. and AllCells, LLC to collaborate with Mount Sinai as part of $8.8 million Grant to Further Stem Cell Research
April 16, 2015 – Icahn School of Medicine at Mount Sinai (ISSMM) will be able to further develop new blood treatments for chemotherapy-resistant blood cancer and other genetic blood disorders thanks to an $8.8 million grant from the New York State Stem …